Hawaiian wetlands provide habitat for seven indigenous waterbirds. Of the six endemic to Hawai‘i, the U.S. Fish and Wildlife Service has designated five as endangered and one as threatened; maintaining their populations requires control of introduced species of predators. Their susceptibility to depredation varies by life stage, and they should be managed strategically to offset vulnerabilities specific to each life stage. A review of the literature for life-stage-specific predators of the eggs, chicks, and adults of the endemic Hawaiian Duck (Anas wyvilliana, koloa maoli), Hawaiian Coot (Fulica alai, ‘alae ke‘oke‘o), Hawaiian Gallinule (Gallinula galeata sandvicensis, ‘alae ‘ula), and Hawaiian Stilt (Himantopus mexicanus knudseni, ae‘o) yielded 99 sources and identified 17 predators, encompassing birds, mammals, reptiles, amphibians, and fish. Eleven species of predators took eggs or chicks; only four took adults. Although some predators may have been reported taking only one of the waterbirds, it is likely they pose at least some risk to all four taxa. However, variation in behavior and habitat among the four waterbirds may lead to slightly different predation pressures. Aquatic predators likely have a propensity for the more aquatic duck, coot, and gallinule chicks. Managers of Hawaiian waterbirds will require many tools and resources to combat predators that occupy land, air, and water, but control should focus on the most devastating taxa—nonnative birds and mammals.