From 2020 to 2024 the population of the Osprey (Pandion haliaetus) nesting in seven counties in central interior California increased at an average annual rate of 4.5%. Of the 13 to 51 nests adequately monitored annually, the percentage that successfully fledged young (nest success) ranged from 69% to 100% per year, while productivity (number of young fledged per occupied nest) ranged from 1.13 to 1.85. Average annual storage levels at the five major reservoirs were roughly associated with Osprey nesting success and productivity over the five-year period, although the relationship was not statistically significant. The rates of reproductive success and productivity we observed are similar to those since 1975 elsewhere in northern California, where success has remained consistently high. The rate of increase of the central interior population is lower than for most other areas studied since 1975, suggesting that the population, although reproducing at or above a sustainable level, may be reaching a habitat-limited carrying capacity. A rapid recent increase in the Bald Eagle (Haliaeetus leucocephalus) population in this region poses a potential threat, but no detrimental effects on the Osprey have been documented yet.